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Could GLP-1 drugs be anti-aging medications?
Researchers found tirzepatide and semaglutide slowed epigenetic aging by up to 1.1 years in trial participants and extended mouse lifespans.
- Recent research indicates GLP-1 drugs, including Wegovy, Ozempic, Zepbound, and Mounjaro, may slow biological aging and potentially extend human lifespan by improving health outcomes beyond weight loss.
- Scientists at the University of California at Berkeley have long known that calorie restriction of about 25% extends animal lifespans. Researchers tested this by comparing GLP-1 injections to calorie restriction in Mice, finding both methods improved longevity.
- Kevin Duffin, vice president of aging research at Eli Lilly, presented Surmount study data on more than 700 adults showing participants using Mounjaro or Zepbound experienced slower biological clock advancement over 72 weeks.
- Novo Nordisk scientists found Wegovy or Ozempic reduced heart biological age by two to four years, with similar benefits for lung, kidney, brain, and pancreas. "We're seeing a reduction in age," Duffin said.
- James Kirkland, director of the Center for Advanced Gerotherapeutics at Cedars-Sinai Medical Center, warns against "biohacking" with these drugs, cautioning it is too early to use medications solely for life extension in healthy individuals.
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28 Articles
28 Articles
Initial research suggests that medications for weight loss and diabetes can affect the biological processes of aging
·São Paulo, Brazil
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