HPV Vaccination Linked to Lower Risk of Pregnancy Complications
Researchers found lower odds of preterm birth and other complications among 624,713 Swedish women vaccinated before pregnancy.
- A new Swedish study published in The BMJ indicates that women vaccinated against HPV before pregnancy face decreased risk of preterm birth, based on analysis of 624,713 first-time mothers between 2006 and 2023.
- Researchers initiated the study following evidence that HPV infections and cervical lesion treatments correlate with increased pregnancy complications, aiming to determine if vaccination might reduce risks including premature rupture of membranes.
- Vaccinated women were 5% less likely to give birth before 37 weeks and 15% less likely to give birth at 28-31 weeks; the study also found an 8% reduced risk of delivering a baby very small for gestational age.
- Lead researcher Zhongsong Zhang, a PhD student at the Karolinska Institute, noted the protective effect was strongest for women vaccinated before age 17, suggesting these findings may strengthen public confidence in HPV vaccination.
- Researchers acknowledged potential 'healthy vaccinee' bias in the observational study, yet emphasized that these findings support continued implementation of HPV vaccination in routine immunization programs globally.
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The HPV vaccine is best known for protecting against cervical cancer, but it may also have another important benefit: reducing the risk of serious complications during pregnancy.
Beyond cancer: Researchers explore another potential benefit of the HPV vaccine
While HPV vaccination is primarily known for preventing cervical cancer, new evidence suggests it may also provide significant benefits for future pregnancies. A study by researchers at the Karolinska Institute, published in The BMJ, indicates that the vaccine may reduce the risk of several dangerous pregnancy complications. The research team, led by Zhang Zhongsheng, analyzed data from over 624,000 births recorded in Swedish national registries…
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